Publicaciones

Population-based screening of Uruguayan Ashkenazi Jews for recurrent BRCA1 and BRCA2 pathogenic sequence variants
Cecilia Castillo Nora Artagaveytia Lucia Brignoni Yael Laitman Natalia Camejo Ana Laura Hernández Gabriel Krygier Alfonso Cayota Lucia Delgado Eitan Friedman

https://pubmed.ncbi.nlm.nih.gov/35332707/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20220326225619&v=2.17.6

Hsa-miR-183-5p Modulates Cell Adhesion by Repression of <em>ITGB1</em> Expression in Prostate Cancer
Carolina Oliveira-Rizzo María Carolina Ottati Rafael Sebastián Fort Santiago Chavez Juan Manuel Trinidad Andrés DiPaolo Beatriz Garat José Roberto Sotelo-Silveira María Ana Duhagon

https://pubmed.ncbi.nlm.nih.gov/35202085/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20220225232131&v=2.17.5

Tracing the Distribution of European Lactase Persistence Genotypes Along the Americas
Ana Cecília Guimarães Alves...

https://pubmed.ncbi.nlm.nih.gov/34630506/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20211011200104&v=2.15.0

Blood cell respiration rates and mtDNA copy number: a promising tool for the diagnosis of mitochondrial disease
Martina Alonso...

https://pubmed.ncbi.nlm.nih.gov/34536563/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210921054941&v=2.14.5

Extensive Translational Regulation through the Proliferative Transition of Trypanosoma cruzi Revealed by Multi-Omics
Santiago Chávez Michael D Urbaniak Corinna Benz Pablo Smircich Beatriz Garat José R Sotelo-Silveira María Ana Duhagon

https://pubmed.ncbi.nlm.nih.gov/34468164/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210902114435&v=2.14.5

Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology
Rafael Sebastián Fort María Ana Duhagon

https://pubmed.ncbi.nlm.nih.gov/34354812/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210808093604&v=2.14.5

CBG Montevideo: A Clinically Novel <em>SERPINA6</em> Mutation Leading to Haploinsufficiency of Corticosteroid-binding Globulin
Emily Jane Meyer Lucía Spangenberg Maria José Ramírez Sunita Maria Christina De Sousa Victor Raggio David James Torpy

https://pubmed.ncbi.nlm.nih.gov/34308089/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210728210929&v=2.14.5

Characterizing the Genetic Architecture of Parkinson's Disease in Latinos
Douglas P Loesch...

https://pubmed.ncbi.nlm.nih.gov/34227697/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210707232652&v=2.14.5

Lost and Found: Piwi and Argonaute Pathways in Flatworms
Santiago Fontenla Gabriel Rinaldi Jose F Tort

https://pubmed.ncbi.nlm.nih.gov/34123869/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210615080920&v=2.14.4

Whole genome sequencing reveals a frameshift mutation and a large deletion in YY1AP1 in a girl with a panvascular artery disease
Víctor Raggio...

https://pubmed.ncbi.nlm.nih.gov/33971976/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210513054235&v=2.14.4

Novel frameshift mutation in PURA gene causes severe encephalopathy of unclear cause
Lucía Spangenberg Rosario Guecaimburú Alejandra Tapié Susana Vivas Soledad Rodríguez Martín Graña Hugo Naya Víctor Raggio

https://pubmed.ncbi.nlm.nih.gov/33750045/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210324085636&v=2.14.3

Ancestry and TPMT-VNTR Polymorphism: Relationship with Hematological Toxicity in Uruguayan Patients with Acute Lymphoblastic Leukemia
Gabriela Burgueño-Rodríguez Yessika Méndez Natalia Olano Agustín Dabezies Bernardo Bertoni Jorge Souto Luis Castillo Julio da Luz Ana María Soler

https://pubmed.ncbi.nlm.nih.gov/33424606/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20210112201210&v=2.14.2

Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer
Carolina Bonilla Bernardo Bertoni Josine L Min Gibran Hemani Genetics of DNA Methylation Consortium Hannah R Elliott

https://pubmed.ncbi.nlm.nih.gov/33248005/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20201129203355&v=2.13.0

Genome-Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients
Elif Irem Sarihan...

https://pubmed.ncbi.nlm.nih.gov/33150996/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20201107005613&v=2.13.0

Discovery of novel DNA methylation biomarkers for non-invasive sporadic breast cancer detection in the Latino population
Mónica Cappetta Lucía Fernandez Lucía Brignoni Nora Artagaveytia Carolina Bonilla Miguel López Manel Esteller Bernardo Bertoni María Berdasco

https://pubmed.ncbi.nlm.nih.gov/33145876/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20201105001051&v=2.13.0

Genomic Diversity in Sporadic Breast Cancer in a Latin American Population
Lucía Brignoni Mónica Cappetta Valentina Colistro Mónica Sans Nora Artagaveytia Carolina Bonilla Bernardo Bertoni

https://pubmed.ncbi.nlm.nih.gov/33126731/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20201031193839&v=2.12.6

Editorial: Novel Frontiers in Helminth Genomics
Jose F Tort Makedonka Mitreva Klaus R Brehm Gabriel Rinaldi

https://pubmed.ncbi.nlm.nih.gov/32922432/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200915233353&v=2.11.5

Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome.
Lewis H, Samanta D, Örsell JL, Bosanko KA, Rowell A, Jones M, Dale RC, Taravath S, Hahn CD, Krishnakumar D, Chagnon S, Keller S, Hagebeuk E, Pathak S, Bebin EM, Arndt DH, Alexander JJ, Mainali G, Coppola G, Maclean J, Sparagana S, McNamara N, Smith DM,...

https://www.ncbi.nlm.nih.gov/pubmed/32446642?dopt=Abstract

Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome
Hannah Lewis...

https://pubmed.ncbi.nlm.nih.gov/32446642/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Design of a Peptide-Carrier Vaccine Based on the Highly Immunogenic Fasciola hepatica Leucine Aminopeptidase.
Salazar C, Tort JF, Carmona C

https://www.ncbi.nlm.nih.gov/pubmed/32399930?dopt=Abstract

Design of a Peptide-Carrier Vaccine Based on the Highly Immunogenic Fasciola hepatica Leucine Aminopeptidase
Cecilia Salazar José F Tort Carlos Carmona

https://pubmed.ncbi.nlm.nih.gov/32399930/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Gene Silencing in the Liver Fluke Fasciola hepatica: RNA Interference.
Rinaldi G, Dell'Oca N, Castillo E, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/32399922?dopt=Abstract

Gene Silencing in the Liver Fluke Fasciola hepatica: RNA Interference
Gabriel Rinaldi Nicolás Dell'Oca Estela Castillo José F Tort

https://pubmed.ncbi.nlm.nih.gov/32399922/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

vtRNA2-1/nc886 Produces a Small RNA That Contributes to Its Tumor Suppression Action through the microRNA Pathway in Prostate Cancer.
Fort RS, Garat B, Sotelo-Silveira JR, Duhagon MA

https://www.ncbi.nlm.nih.gov/pubmed/32093270?dopt=Abstract

vtRNA2-1/nc886 Produces a Small RNA That Contributes to Its Tumor Suppression Action through the microRNA Pathway in Prostate Cancer
Rafael Sebastián Fort Beatriz Garat José Roberto Sotelo-Silveira María Ana Duhagon

https://pubmed.ncbi.nlm.nih.gov/32093270/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Effect of 15 BMI-Associated Polymorphisms, Reported for Europeans, across Ethnicities and Degrees of Amerindian Ancestry in Mexican Children.
Costa-Urrutia P, Abud C, Franco-Trecu V, Colistro V, Rodríguez-Arellano ME, Alvarez-Fariña R, Acuña Alonso V, Bertoni B, Granados J

https://www.ncbi.nlm.nih.gov/pubmed/31936053?dopt=Abstract

Effect of 15 BMI-Associated Polymorphisms, Reported for Europeans, across Ethnicities and Degrees of Amerindian Ancestry in Mexican Children
Paula Costa-Urrutia Carolina Abud Valentina Franco-Trecu Valentina Colistro Martha Eunice Rodríguez-Arellano Rafael Alvarez-Fariña Víctor Acuña Alonso Bernardo Bertoni Julio Granados

https://pubmed.ncbi.nlm.nih.gov/31936053/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Malignant Infantile osteopetrosis.
Vomero A, Tapie A, Arroyo C, Raggio V, Peluffo G, Dufort G

https://www.ncbi.nlm.nih.gov/pubmed/31859718?dopt=Abstract

Malignant Infantile osteopetrosis
A Vomero A Tapie C Arroyo V Raggio G Peluffo G Dufort

https://pubmed.ncbi.nlm.nih.gov/31859718/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

The influence of polymorphisms of xenobiotic-metabolizing and DNA repair genes in DNA damage, telomere length and global DNA methylation evaluated in open-cast coal mining workers.
de Souza MR, Rohr P, Kahl VFS, Kvitko K, Cappetta M, Lopes WM, Simon D, da Silva J

https://www.ncbi.nlm.nih.gov/pubmed/31787382?dopt=Abstract

The influence of polymorphisms of xenobiotic-metabolizing and DNA repair genes in DNA damage, telomere length and global DNA methylation evaluated in open-cast coal mining workers
Melissa Rosa de Souza Paula Rohr Vivian Francília Silva Kahl Kátia Kvitko Mónica Cappetta Wilner Martinez Lopes Daniel Simon Juliana da Silva

https://pubmed.ncbi.nlm.nih.gov/31787382/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Compositional Analysis of Flatworm Genomes Shows Strong Codon Usage Biases Across All Classes.
Lamolle G, Fontenla S, Rijo G, Tort JF, Smircich P

https://www.ncbi.nlm.nih.gov/pubmed/31543897?dopt=Abstract

Compositional Analysis of Flatworm Genomes Shows Strong Codon Usage Biases Across All Classes
Guillermo Lamolle Santiago Fontenla Gastón Rijo Jose F Tort Pablo Smircich

https://pubmed.ncbi.nlm.nih.gov/31543897/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Adaptive radiation of the flukes of the family Fasciolidae inferred from genome-wide comparisons of key species.
Choi YJ, Fontenla S, Fischer PU, Le TH, Costábile A, Blair D, Brindley PJ, Tort JF, Cabada MM, Mitreva M

https://www.ncbi.nlm.nih.gov/pubmed/31501870?dopt=Abstract

Adaptive Radiation of the Flukes of the Family Fasciolidae Inferred from Genome-Wide Comparisons of Key Species
Young-Jun Choi Santiago Fontenla Peter U Fischer Thanh Hoa Le Alicia Costábile David Blair Paul J Brindley Jose F Tort Miguel M Cabada Makedonka Mitreva

https://pubmed.ncbi.nlm.nih.gov/31501870/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Mutation update for the SATB2 gene.
Zarate YA, Bosanko KA, Caffrey AR, Bernstein JA, Martin DM, Williams MS, Berry-Kravis EM, Mark PR, Manning MA, Bhambhani V, Vargas M, Seeley AH, Estrada-Veras JI, van Dooren MF, Schwab M, Vanderver A, Melis D, Alsadah A, Sadler L, Van Esch H,...

https://www.ncbi.nlm.nih.gov/pubmed/31021519?dopt=Abstract

Mutation update for the SATB2 gene
Yuri A Zarate...

https://pubmed.ncbi.nlm.nih.gov/31021519/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Anthropogenic Effects on Natural Mammalian Populations: Correlation Between Telomere Length and Coal Exposure.
Matzenbacher CA, Da Silva J, Garcia ALH, Cappetta M, de Freitas TRO

https://www.ncbi.nlm.nih.gov/pubmed/31004106?dopt=Abstract

Anthropogenic Effects on Natural Mammalian Populations: Correlation Between Telomere Length and Coal Exposure
Cristina A Matzenbacher Juliana Da Silva Ana Leticia H Garcia Mónica Cappetta Thales R O de Freitas

https://pubmed.ncbi.nlm.nih.gov/31004106/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Cathepsin L3 From Fasciola hepatica Induces NLRP3 Inflammasome Alternative Activation in Murine Dendritic Cells.
Celias DP, Corvo I, Silvane L, Tort JF, Chiapello LS, Fresno M, Arranz A, Motrán CC, Cervi L

https://www.ncbi.nlm.nih.gov/pubmed/30967874?dopt=Abstract

Cathepsin L3 From <em>Fasciola hepatica</em> Induces NLRP3 Inflammasome Alternative Activation in Murine Dendritic Cells
Daiana Pamela Celias Ileana Corvo Leonardo Silvane José Francisco Tort Laura Silvina Chiapello Manuel Fresno Alicia Arranz Claudia Cristina Motrán Laura Cervi

https://pubmed.ncbi.nlm.nih.gov/30967874/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth.
Pereyra S, Sosa C, Bertoni B, Sapiro R

https://www.ncbi.nlm.nih.gov/pubmed/30935390?dopt=Abstract

Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth
Silvana Pereyra Claudio Sosa Bernardo Bertoni Rossana Sapiro

https://pubmed.ncbi.nlm.nih.gov/30935390/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Shorter telomere length and DNA hypermethylation in peripheral blood cells of coal workers.
de Souza MR, Kahl VFS, Rohr P, Kvitko K, Cappetta M, Lopes WM, da Silva J

https://www.ncbi.nlm.nih.gov/pubmed/30442342?dopt=Abstract

Shorter telomere length and DNA hypermethylation in peripheral blood cells of coal workers
Melissa Rosa de Souza Vivian Francília Silva Kahl Paula Rohr Kátia Kvitko Mónica Cappetta Wilner Martinez Lopes Juliana da Silva

https://pubmed.ncbi.nlm.nih.gov/30442342/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Deep sequencing discovery of causal mtDNA mutations in a patient with unspecific neurological disease.
Spangenberg L, Graña M, Mansilla S, Martínez J, Tapié A, Greif G, Montano N, Vaglio A, Gueçaimburú R, Robello C, Castro L, Quijano C, Raggio V, Naya H

https://www.ncbi.nlm.nih.gov/pubmed/30227252?dopt=Abstract

Deep sequencing discovery of causal mtDNA mutations in a patient with unspecific neurological disease
Lucía Spangenberg...

https://pubmed.ncbi.nlm.nih.gov/30227252/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Isolation and Structural Characterization of Bioactive Molecules on Prostate Cancer from Mayan Traditional Medicinal Plants.
Fort RS, Trinidad Barnech JM, Dourron J, Colazzo M, Aguirre-Crespo FJ, Duhagon MA, Álvarez G

https://www.ncbi.nlm.nih.gov/pubmed/30110911?dopt=Abstract

Isolation and Structural Characterization of Bioactive Molecules on Prostate Cancer from Mayan Traditional Medicinal Plants
Rafael Sebastián Fort Juan M Trinidad Barnech Juliette Dourron Marcos Colazzo Francisco J Aguirre-Crespo María Ana Duhagon Guzmán Álvarez

https://pubmed.ncbi.nlm.nih.gov/30110911/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Different SNPs in Fasciola hepatica P-glycoprotein from diverse Latin American populations are not associated with Triclabendazole resistance.
Solana MV, Domínguez MF, Scarcella S, Radio S, Smircich P, Fernández S, Solana H, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/30055185?dopt=Abstract

Different SNPs in Fasciola hepatica P-glycoprotein from diverse Latin American populations are not associated with Triclabendazole resistance
María Victoria Solana María Fernanda Domínguez Silvana Scarcella Santiago Radio Pablo Smircich Silvina Fernández Hugo Solana José F Tort

https://pubmed.ncbi.nlm.nih.gov/30055185/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability.
Kahl VFS, Dhillon V, Fenech M, de Souza MR, da Silva FN, Marroni NAP, Nunes EA, Cerchiaro G, Pedron T, Batista BL, Cappetta M, Mártinez-López W, Simon D, da Silva J

https://www.ncbi.nlm.nih.gov/pubmed/29967663?dopt=Abstract

Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability
Vivian F Silva Kahl...

https://pubmed.ncbi.nlm.nih.gov/29967663/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer.
Fort RS, Mathó C, Oliveira-Rizzo C, Garat B, Sotelo-Silveira JR, Duhagon MA

https://www.ncbi.nlm.nih.gov/pubmed/29744254?dopt=Abstract

An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer
Rafael Sebastián Fort Cecilia Mathó Carolina Oliveira-Rizzo Beatriz Garat José Roberto Sotelo-Silveira María Ana Duhagon

https://pubmed.ncbi.nlm.nih.gov/29744254/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Substrate Specificity of Cysteine Proteases Beyond the S2 Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L.
Corvo I, Ferraro F, Merlino A, Zuberbühler K, O'Donoghue AJ, Pastro L, Pi-Denis N, Basika T, Roche L, McKerrow JH, Craik CS, Caffrey CR, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/29725596?dopt=Abstract

Substrate Specificity of Cysteine Proteases Beyond the S<sub>2</sub> Pocket: Mutagenesis and Molecular Dynamics Investigation of <em>Fasciola hepatica</em> Cathepsins L
Ileana Corvo...

https://pubmed.ncbi.nlm.nih.gov/29725596/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20200901155609&v=2.11.5

Chronic occupational exposure endured by tobacco farmers from Brazil and association with DNA damage.
Kahl VFS, Dhillon VS, Simon D, da Silva FR, Salvador M, Branco CDS, Cappetta M, Martínez-López W, Thiesen FV, Dias JF, Souza CT, Fenech M, da Silva J

https://www.ncbi.nlm.nih.gov/pubmed/29669110?dopt=Abstract

Chronic occupational exposure endured by tobacco farmers from Brazil and association with DNA damage
Vívian F Silva Kahl...

https://pubmed.ncbi.nlm.nih.gov/29669110/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1lmtEnFQ0PPAI7BwWbmE7p5niiTpU0TDh3ZhatK3TrIR2ETEES&fc=20200831230301&ff=20201029172838&v=2.12.6

Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth.
Fort RS, Mathó C, Geraldo MV, Ottati MC, Yamashita AS, Saito KC, Leite KRM, Méndez M, Maedo N, Méndez L, Garat B, Kimura ET, Sotelo-Silveira JR, Duhagon MA

https://www.ncbi.nlm.nih.gov/pubmed/29394925?dopt=Abstract

Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs.
Radio S, Fontenla S, Solana V, Matos Salim AC, Araújo FMG, Ortiz P, Hoban C, Miranda E, Gayo V, Pais FS, Solana H, Oliveira G, Smircich P, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/29368659?dopt=Abstract

Erratum: Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry.
Cornejo-Olivas M, Torres L, Velit-Salazar MR, Inca-Martinez M, Mazzetti P, Cosentino C, Micheli F, Perandones C, Dieguez E, Raggio V, Tumas V, Borges V, Ferraz HB, Rieder CRM, Shumacher-Schuh A, Velez-Pardo C, Jimenez-Del-Rio M, Lopera F, Chang...

https://www.ncbi.nlm.nih.gov/pubmed/29367946?dopt=Abstract

DNA damage and epigenetic alteration in soybean farmers exposed to complex mixture of pesticides.
Benedetti D, Lopes Alderete B, de Souza CT, Ferraz Dias J, Niekraszewicz L, Cappetta M, Martínez-López W, Da Silva J

https://www.ncbi.nlm.nih.gov/pubmed/29244183?dopt=Abstract

Transcriptome-wide analysis of the Trypanosoma cruzi proliferative cycle identifies the periodically expressed mRNAs and their multiple levels of control.
Chávez S, Eastman G, Smircich P, Becco LL, Oliveira-Rizzo C, Fort R, Potenza M, Garat B, Sotelo-Silveira JR, Duhagon MA

https://www.ncbi.nlm.nih.gov/pubmed/29182646?dopt=Abstract

Expression, purification and characterization of two leucine aminopeptidases of the blood fluke, Schistosoma mansoni.
Maggioli G, Rinaldi G, Giaudrone I, Berasain P, Tort JF, Brindley PJ, Carmona C

https://www.ncbi.nlm.nih.gov/pubmed/29169803?dopt=Abstract

Conservation and diversification of small RNA pathways within flatworms.
Fontenla S, Rinaldi G, Smircich P, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/28893179?dopt=Abstract

Associations between male infertility and ancestry in South Americans: a case control study.
Skowronek MF, Velazquez T, Mut P, Figueiro G, Sans M, Bertoni B, Sapiro R

https://www.ncbi.nlm.nih.gov/pubmed/28747152?dopt=Abstract

Prevalence of EGFR Mutations in Lung Cancer in Uruguayan Population.
Berois N, Touya D, Ubillos L, Bertoni B, Osinaga E, Varangot M

https://www.ncbi.nlm.nih.gov/pubmed/28744312?dopt=Abstract

Functional characterization of single-domain cystatin-like cysteine proteinase inhibitors expressed by the trematode Fasciola hepatica.
Cancela M, Corvo I, DA Silva E, Teichmann A, Roche L, Díaz A, Tort JF, Ferreira HB, Zaha A

https://www.ncbi.nlm.nih.gov/pubmed/28697819?dopt=Abstract

Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry.
Cornejo-Olivas M, Torres L, Velit-Salazar MR, Inca-Martinez M, Mazzetti P, Cosentino C, Micheli F, Perandones C, Dieguez E, Raggio V, Tumas V, Borges V, Ferraz HB, Rieder CRM, Shumacher-Schuh A, Velez-Pardo C, Jimenez-Del-Rio M, Lopera F, Chang...

https://www.ncbi.nlm.nih.gov/pubmed/28649619?dopt=Abstract

Nuclear Compartmentalization Contributes to Stage-Specific Gene Expression Control in Trypanosoma cruzi.
Pastro L, Smircich P, Di Paolo A, Becco L, Duhagon MA, Sotelo-Silveira J, Garat B

https://www.ncbi.nlm.nih.gov/pubmed/28243589?dopt=Abstract

A novel mutation in the OAR domain of the ARX gene.
Tapie A, Pi-Denis N, Souto J, Vomero A, Peluffo G, Boidi M, Ciganda M, Curbelo N, Raggio V, Roche L, Pastro L

https://www.ncbi.nlm.nih.gov/pubmed/28174645?dopt=Abstract

Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers.
McNulty SN, Tort JF, Rinaldi G, Fischer K, Rosa BA, Smircich P, Fontenla S, Choi YJ, Tyagi R, Hallsworth-Pepin K, Mann VH, Kammili L, Latham PS, Dell'Oca N, Dominguez F, Carmona C, Fischer PU, Brindley PJ, Mitreva M

https://www.ncbi.nlm.nih.gov/pubmed/28060841?dopt=Abstract

Fasciolosis in South America: epidemiology and control challenges.
Carmona C, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/27608827?dopt=Abstract

Identification of Chalcones as Fasciola hepatica Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach.
Ferraro F, Merlino A, Dell Oca N, Gil J, Tort JF, Gonzalez M, Cerecetto H, Cabrera M, Corvo I

https://www.ncbi.nlm.nih.gov/pubmed/27463369?dopt=Abstract

Interactions between environmental factors and maternal-fetal genetic variations: strategies to elucidate risks of preterm birth.
Pereyra S, Bertoni B, Sapiro R

https://www.ncbi.nlm.nih.gov/pubmed/27156152?dopt=Abstract

3697G>A in MT-ND1 is a causative mutation in mitochondrial disease.
Spangenberg L, Graña M, Greif G, Suarez-Rivero JM, Krysztal K, Tapié A, Boidi M, Fraga V, Lemes A, Gueçaimburú R, Cerisola A, Sánchez-Alcázar JA, Robello C, Raggio V, Naya H

https://www.ncbi.nlm.nih.gov/pubmed/27017994?dopt=Abstract

Conserved Curvature of RNA Polymerase I Core Promoter Beyond rRNA Genes: The Case of the Tritryps.
Smircich P, Duhagon MA, Garat B

https://www.ncbi.nlm.nih.gov/pubmed/26718450?dopt=Abstract

Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.
Caley MP, King H, Shah N, Wang K, Rodriguez-Teja M, Gronau JH, Waxman J, Sturge J

https://www.ncbi.nlm.nih.gov/pubmed/26567111?dopt=Abstract

The miRnome of Fasciola hepatica juveniles endorses the existence of a reduced set of highly divergent micro RNAs in parasitic flatworms.
Fontenla S, Dell'Oca N, Smircich P, Tort JF, Siles-Lucas M

https://www.ncbi.nlm.nih.gov/pubmed/26432296?dopt=Abstract

Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi.
Smircich P, Eastman G, Bispo S, Duhagon MA, Guerra-Slompo EP, Garat B, Goldenberg S, Munroe DJ, Dallagiovanna B, Holetz F, Sotelo-Silveira JR

https://www.ncbi.nlm.nih.gov/pubmed/26054634?dopt=Abstract

Effect of genetic ancestry on leukocyte global DNA methylation in cancer patients.
Cappetta M, Berdasco M, Hochmann J, Bonilla C, Sans M, Hidalgo PC, Artagaveytia N, Kittles R, Martínez M, Esteller M, Bertoni B

https://www.ncbi.nlm.nih.gov/pubmed/26012346?dopt=Abstract

Molecular characterization of genes modifying the age at onset in Huntington's disease in Uruguayan patients.
Vital M, Bidegain E, Raggio V, Esperon P

https://www.ncbi.nlm.nih.gov/pubmed/26000918?dopt=Abstract

Breast cancer risk and genetic ancestry: a case-control study in Uruguay.
Bonilla C, Bertoni B, Hidalgo PC, Artagaveytia N, Ackermann E, Barreto I, Cancela P, Cappetta M, Egaña A, Figueiro G, Heinzen S, Hooker S, Román E, Sans M, Kittles RA

https://www.ncbi.nlm.nih.gov/pubmed/25783644?dopt=Abstract

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.
Rodriguez-Teja M, Gronau JH, Breit C, Zhang YZ, Minamidate A, Caley MP, McCarthy A, Cox TR, Erler JT, Gaughan L, Darby S, Robson C, Mauri F, Waxman J, Sturge J

https://www.ncbi.nlm.nih.gov/pubmed/25408555?dopt=Abstract

Survival Outcome and EMT Suppression Mediated by a Lectin Domain Interaction of Endo180 and CD147.
Rodriguez-Teja M, Gronau JH, Minamidate A, Darby S, Gaughan L, Robson C, Mauri F, Waxman J, Sturge J

https://www.ncbi.nlm.nih.gov/pubmed/25381222?dopt=Abstract

RNA interference in Fasciola hepatica newly excysted juveniles: long dsRNA induces more persistent silencing than siRNA.
Dell'Oca N, Basika T, Corvo I, Castillo E, Brindley PJ, Rinaldi G, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/25307443?dopt=Abstract

Allelic frequencies and statistical data from 30 INDEL loci in Uruguayan population.
Saiz M, André F, Pisano N, Sandberg N, Bertoni B, Pagano S

https://www.ncbi.nlm.nih.gov/pubmed/23953140?dopt=Abstract

Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.
Corvo I, O'Donoghue AJ, Pastro L, Pi-Denis N, Eroy-Reveles A, Roche L, McKerrow JH, Dalton JP, Craik CS, Caffrey CR, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/23875031?dopt=Abstract

Concomitant detection of BCR-ABL translocation and JAK2 V617F mutation in five patients with myeloproliferative neoplasm at diagnosis.
Cappetta M, Pérez V, Zubillaga MN, Elizondo V, Manrique G, Prosper I, Boschi S, Bonomi R, Pomoli S, Díaz L, Martínez L, Uriarte MR

https://www.ncbi.nlm.nih.gov/pubmed/23062104?dopt=Abstract

The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen.
Corvo I, Cancela M, Cappetta M, Pi-Denis N, Tort JF, Roche L

https://www.ncbi.nlm.nih.gov/pubmed/19383516?dopt=Abstract

A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica.
Cancela M, Acosta D, Rinaldi G, Silva E, Durán R, Roche L, Zaha A, Carmona C, Tort JF

https://www.ncbi.nlm.nih.gov/pubmed/18573308?dopt=Abstract

Directional mating and a rapid male population expansion in a hybrid Uruguayan population.
Bertoni B, Jin L, Chakraborty R, Sans M

https://www.ncbi.nlm.nih.gov/pubmed/16254907?dopt=Abstract

(GCG)11 founder mutation in the PABPN1 gene of OPMD Uruguayan families.
Rodríguez M, Camejo C, Bertoni B, Braida C, Rodríguez MM, Brais B, Medici M, Roche L

https://www.ncbi.nlm.nih.gov/pubmed/15694141?dopt=Abstract

Admixture in Hispanics: distribution of ancestral population contributions in the Continental United States.
Bertoni B, Budowle B, Sans M, Barton SA, Chakraborty R

https://www.ncbi.nlm.nih.gov/pubmed/12713142?dopt=Abstract

Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain.
Cappetta M, Roth I, Díaz A, Tort J, Roche L

https://www.ncbi.nlm.nih.gov/pubmed/12437108?dopt=Abstract